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Presence and Extent of Severe Facet Joint Osteoarthritis Are Associated with Back Pain in Older Adults

机译:重度小关节骨关节炎的存在和程度与老年人的腰痛相关

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摘要

Objective\ud\udTo determine whether the presence and extent of severe lumbar facet joint osteoarthritis (OA) are associated with back pain in older adults, accounting for disc height narrowing and other covariates.\ud\udDesign\ud\udTwo hundred and fifty-two older adults from the Framingham Offspring Cohort (mean age 67 years) were studied. Participants received standardized computed tomography (CT) assessments of lumbar facet joint OA and disc height narrowing at the L2–S1 interspaces using four-grade semi-quantitative scales. Severe facet joint OA was defined according to the presence and/or degree of joint space narrowing, osteophytosis, articular process hypertrophy, articular erosions, subchondral cysts, and intraarticular vacuum phenomenon. Severe disc height narrowing was defined as marked narrowing with endplates almost in contact. Back pain was defined as participant report of pain on most days or all days in the past 12 months. We used multivariable logistic regression to examine associations between severe facet joint OA and back pain, adjusting for key covariates including disc height narrowing, sociodemographics, anthropometrics, and health factors.\ud\udResults\ud\udSevere facet joint OA was more common in participants with back pain than those without (63.2% vs 46.7%; P = 0.03). In multivariable analyses, presence of any severe facet joint OA remained significantly associated with back pain (odds ratio (OR) 2.15 [95% confidence interval (CI) 1.13–4.08]). Each additional joint with severe OA conferred greater odds of back pain [OR per joint 1.20 (95% CI 1.02–1.41)].\ud\udConclusions\ud\udThe presence and extent of severe facet joint OA on CT imaging are associated with back pain in community-based older adults, independent of sociodemographics, health factors, and disc height narrowing.
机译:目的\ ud \ ud确定老年人严重腰椎小关节骨关节炎(OA)的存在和程度是否与腰背痛有关,并解释椎间盘高度变窄和其他协变量。\ ud \ udDesign \ ud \ ud250研究了来自弗雷明汉后代队列的两名老年人(平均年龄67岁)。参与者使用四级半定量量表对腰椎小关节OA和L2–S1间隙的椎间盘高度变窄进行了标准计算机断层扫描(CT)评估。根据关节间隙变窄,骨赘,关节突肥大,关节糜烂,软骨下囊肿和关节内真空现象的存在和/或程度,定义了严重的小关节OA。严重的椎间盘高度变窄定义为端板几乎接触时明显变窄。背痛定义为参与者在过去12个月中大部分或整天的疼痛报告。我们使用多变量logistic回归分析了严重的小关节OA与背部疼痛之间的关联,并调整了关键协变量,包括椎间盘高度变窄,社会人口统计学,人体测量学和健康因素。\ ud \ udResults \ ud \ ud背痛的发生率比没有背痛的发生率高(分别为63.2%和46.7%; P = 0.03)。在多变量分析中,任何严重的小关节OA的存在仍然与背痛显着相关(优势比(OR)为2.15 [95%置信区间(CI)为1.13-4.08])。每增加一个具有严重OA的关节都会带来更大的背痛几率[每个关节的OR为1.20(95%CI 1.02-1.41)]。\ ud \ ud结论\ ud \ udCT成像中严重的小关节OA的存在和程度与背部相关基于社区的老年人的疼痛,与社会人口统计学,健康因素和椎间盘高度变窄无关。

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